In Week 16, the (6-8) Kansas City Chiefs will hit the road to face the Tennessee Titans at Nissan Stadium in Nashville, Tennessee. The matchup of AFC teams eliminated from playoff contention will kick off at 12 p.m. Arrowhead Time. According to FanDuel Sportsbook, the Chiefs have opened as a 4.5-point favorite for the game. […]
The Jaguars entered Week 15 with a 9-4 record and holding onto the top spot in the AFC South. The Texans and Colts are both on their heels at 8-5, and the Colts trotted out literal grandfather Philip Rivers in the hopes of saving their season. The 2-11 Titans, unsurprisingly, are bringing up the rear […]
There are no style points in the NFL. Whether the San Francisco 49ers win by 21 or two today, they need to win. Historically speaking, Kyle Shanahan’s teams have performed quite well after the bye week. Today’s spot against the Tennessee Titans sets up well. You have one coming off their second win of the […]
The Tennessee Titans head out to San Francisco (well, technically Santa Clara) to take on the 49ers today. On paper, the Titans don’t have much of a chance in this one. The 49ers are a 12.5-point favorite and are the much better team. But, as Kenny Mayne used to say, games aren’t played on paper; […]
The San Francisco 49ers added defensive tackle Jordan Elliott to the injury report due to a knee injury. He will not play today against the Tennessee Titans. It’s an injury that happened at some point today, according to the communications team. Here’s a look at today’s inactives for the 49ers: RB Jordan JamesWR Jordan WatkinsDT […]
The San Francisco 49ers will look to extend their three-game winning streak on Sunday when they host the 2-11 Tennessee Titans at Levi’s Stadium. Kickoff is slated for 1:25 p.m. The 49ers are right in the wildcard mix in the NFC, currently listed as the No. 6 seed in the standings with four games to […]
The Cleveland Browns head into Week 15’s action with the fourth overall pick in the 2026 NFL draft order, as well as the Jacksonville Jaguars selection late in the first round. After Week 14’s loss to the Tennessee Titans, all possibilities are available to the Browns, especially with their difficult finishing schedule. Besides their own […]
The San Francisco 49ers began their winning streak after we started making weekly predictions. Coincidence? I think not. Let’s keep the good vibes rolling and discuss what we expect in Week 15 against the Tennessee Titans. Kyle’s prediction – 49ers 31, Titans 17 For the second time since 1970, the NFL’s most sacked quarterback goes […]
Sportsbooks expect the San Francisco 49ers (9-4) will keep their three-game winning streak alive, as they are favored by 12.5 points in a matchup with the Tennessee Titans (2-11) on Sunday, December 14, 2025 at Levi’s Stadium.
49ers vs. Titans Game Info
When: Sunday, December 14, 2025 at 4:25 p.m. ET
Where: Levi’s Stadium in Santa Clara, California
TV info: FOX
49ers vs. Titans Odds
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It’s been a busy afternoon for the San Francisco 49ers. Christian McCaffrey was added to the injury report, but is expected to play. Meanwhile, we may have seen the last of Brandon Aiyuk in a Niners uniform. As for Sunday’s game against the Tennessee Titans, the 49ers made a couple of moves ahead of that […]
The NFL can be a cruel league. Players are waived, released, or cut based on a numbers crunch, injuries, or in the search for an upgrade. Sometimes players can spend time on a practice squad waiting for a chance that doesn’t come, and move on to greener pastures or another opportunity. Whatever the reason may […]
The New Orleans Saints have remained in the top 3 for a while, but last week they posted a rare win, resulting in some movement. The Tennessee Titans also earned a victory, which was significant for the Saints, but going into Week 15, New Orleans now has the #5 overall pick in the draft. Here […]
(paywall) 49ers vs. Titans: The Standard’s 5 fast predictions (paywall)“Kawakami: 49ers 30, Titans 13. They’re rested, they’ve got most of their main offensive stars back, they’re facing one of the worst teams in the league — this should fall into 49ers-pick-a-score territory unless there’s a major letdown. I don’t think there’ll be a letdown.“ Eric […]
At 4:25 p.m. ET on Sunday, the Tennessee Titans (2-11) play at the San Francisco 49ers (9-4). When these two teams square off, who are the best DFS choices? Find out below.
49ers vs. Titans Game Info
When: Sunday, December 14, 2025 at 4:25 p.m. ET
Where: Levi’s Stadium in Santa Clara, California
TV info: FOX
Live Stream: Watch this game on Fubo (Regional restrictions apply)
49ers DFS Projections
Salary values from DraftKings.
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The San Francisco 49ers are fresh off their bye week, looking to take on the Tennessee Titans on Sunday as they hope to improve to 10-4 in the crowded NFC West picture. Heading into the weekend, the 49ers are one of the biggest favorites in Week 14, coming in as 12.5-point favorites over the 2-11 […]
The Tennessee Titans are coming off their best offensive line performance of the campaign. The Titans rushed for 184 yards in Sunday’s 31-29 Week 14 victory over the Cleveland Browns. Tony Pollard rushed for a career-high 161 yards and two touchdowns, scores of 65 and 32 yards respectively. Rookie quarterback Cam Ward was sacked just […]
Robert Saleh, Klay Kubiak, Brock Purdy preview 49ers-Titans Week 15 matchup“I think Friday’s nice just in terms of having just about everything in when it comes to like our game plan. Obviously, we’ll have first, second down, third down, red zone, everything. And so, Friday being able to compartmentalize everything and go over everything mentally […]
The San Francisco 49ers (9-4) host the Tennessee Titans (2-11) on Sunday, December 14, 2025 at Levi’s Stadium and will attempt to extend a three-game winning streak. Check out the best bets.
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Best Over/Under Bet
O/U Pick: Under (44.5)
The 49ers have played seven games with over 44.5 points scored this season, their current matchup’s over/under.
Six of the Titans’ 13 games this season have had more than 4...
The San Francisco 49ers (9-4) take a three-game winning streak into a matchup with the Tennessee Titans (2-11) on Sunday, December 14, 2025 at Levi’s Stadium.
The 49ers are totaling 341.2 yards per game on offense (11th in NFL), and they rank 20th on defense with 335.8 yards allowed per game. The Titans have not been getting things done on offense, ranking worst with 246.2 total yards per game. They have been more effective on defense, allowing 350.9 total yards per contest (26th-ranked).
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The Cleveland Browns will play their penultimate road game of the season on Sunday against the Chicago Bears. Cleveland is coming off a loss to the one-win Tennessee Titans in a game where the offense actually did something. Meanwhile, the Bears lost to the Green Bay Packers to fall from the No. 1 seed in […]
The San Francisco 49ers are refreshed following their bye week. The defense could return defensive lineman Yetur Gross-Matos, which is a welcome sight for a pass rush that can use all the help it can get down the stretch. Meanwhile, the offense is as healthy as it can be minus Brandon Aiyuk and ready to […]
Former Pittsburgh Steelers defensive back Desmond King has announced his retirement via X. “Officially retired! Bolt up,” King posted. The University of Iowa product was drafted in the fifth round of the 2017 NFL Draft by the Los Angeles Chargers. He was traded to the Tennessee Titans in 2020 and signed as a free agent […]
If you traveled through the New England Patriots media landscape this week, chances are you came across this at some point: Mike Vrabel went a perfect 6-0 coming off a bye week during his time as head coach of the Tennessee Titans, and will have a chance to improve to 7-0 this Sunday against the […]
49ers vs. Titans injury report: 6 players miss Wednesday’s practice“[Eric Kendricks] got a tight calf today, so I’m not sure how much he’s going to go today—if he’s going to go,” Shanahan said. “But he’s working back into here. Hopefully, it’s not too bad of a setback with that, but we’ll see him when he […]
Welcome to SB Nation Reacts, a survey of fans across the NFL. Throughout the year we ask questions of the most plugged-in Browns fans and fans across the country. Sign up here to participate in the weekly emailed surveys. As frustrating as the loss was to the Tennessee Titans this week, I am once again […]