The Los Angeles Rams (6-2) are favored by 5.5 points as they aim to keep their three-game winning streak intact in a game versus the San Francisco 49ers (6-3) on Sunday, November 9, 2025 at Levi’s Stadium.
Rams vs. 49ers Game Info
When: Sunday, November 9, 2025 at 4:25 p.m. ET
Where: Levi’s Stadium in Santa Clara, California
TV info: FOX
Rams vs. 49ers Odds
Favorite
Total
Los Angeles Moneyline
San Francisco Moneyline
BetMGM
Rams (-6)
49.5
-250
...
The San Francisco 49ers have a rivalry matchup ahead of them this weekend, taking on the Los Angeles Rams at Levi’s Stadium on Sunday. Kickoff is slated for 1:25 p.m. The 49ers are prepared to start quarterback Mac Jones for the sixth straight week and eighth time this year, as Brock Purdy continues to recover […]
The Los Angeles Rams are 6-2 and have positioned themselves well in the NFC playoff picture. Their next two games might be their most important of the season so far. They’ll travel to take on the San Francisco 49ers this weekend and then on deck are the Seattle Seahawks at SoFi Stadium. While fans feel […]
The San Francisco 49ers may want Brock Purdy to start Sunday against the Los Angeles Rams, but he’s recovering from an injury. Maybe he’s getting pushed this week, but he’s recovering from an injury. And yes, he could still dress as QB2 — because he’s recovering from an injury. That’s it. No quarterback controversy, no […]
So, it seems like people hated this past Thursday Night Football game between the Las Vegas Raiders and the Denver Broncos, and it was a messy game, but here’s why I enjoyed Thursday’s game: I didn’t know who would win. I believe it was the Thursday prior where we saw the Baltimore Ravens just own […]
Week 1o has the Los Angeles Rams (6-2) traveling to Levi’s Stadium in Santa Clara Ca. for a Sunday November 9 matchup with their arch nemesis, the San Francisco 49ers (6-3). Kickoff is scheduled for 1:25 PST. L.A. is looking not only to tighten its grip on the top spot in the NFC West, but […]
Will Matthew Stafford get into the end zone when the Los Angeles Rams and the San Francisco 49ers meet in Week 10 on Sunday at 4:25 p.m. ET? In the piece below, we dive into his anytime TD player prop, giving you all of the stats and trends you need.
There are prop bets available for Los Angeles Rams QB Stafford in his upcoming game (versus the San Francisco 49ers) — see below for more information.
Matthew Stafford’s Anytime TD Prop Odds vs. the 49ers
Stafford’s odds to score a TD in thi...
Should you wager on Puka Nacua scoring a touchdown in the Los Angeles Rams’ upcoming Week 10 matchup against the San Francisco 49ers, which starts at 4:25 p.m. ET on Sunday? Keep reading for an in-depth look at how he stacks up against his anytime touchdown player prop this week.
Like to place a prop bet on wide receiver Nacua when his Los Angeles Rams play the San Francisco 49ers? The wagers available are listed here.
Puka Nacua’s Anytime TD Prop Odds vs. the 49ers
Nacua’s odds to score...
Will Mac Jones hit paydirt when the San Francisco 49ers and the Los Angeles Rams play in Week 10 on Sunday at 4:25 p.m. ET? In the column below, we dig into his anytime TD player prop, providing you with all of the numbers and trends you need.
There are prop bets available for San Francisco 49ers quarterback Jones in his upcoming game (against the Los Angeles Rams) — see below for more info.
Mac Jones’ Anytime TD Prop Odds vs. the Rams
Jones’ odds to score a TD in this game: +1000 (Bet $...
With the Los Angeles Rams playing the San Francisco 49ers in Week 10 (Sunday at 4:25 p.m. ET), is Davante Adams a good bet to score a touchdown? Below, we break down the odds and stats to determine how well this matchup sets up for him and his anytime touchdown player prop.
Want to place a prop bet on wide receiver Adams when his Los Angeles Rams face the San Francisco 49ers? The wagers available are listed here.
Davante Adams’ Anytime TD Prop Odds vs. the 49ers
Adams’ odds to score a TD...
At 4:25 p.m. ET on Sunday, the San Francisco 49ers (6-3) are at home against the Los Angeles Rams (6-2). Who are the top players to consider from a DFS perspective when these two teams duke it out? Read on to find out.
Rams vs. 49ers Game Info
When: Sunday, November 9, 2025 at 4:25 p.m. ET
Where: Levi’s Stadium in Santa Clara, California
TV info: FOX
Live Stream: Watch this game on Fubo (Regional restrictions apply)
Rams DFS Projections
Salary values from DraftKings.
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The Seattle Seahawks remain atop the NFC West and have another crucial game ahead. The Los Angeles Rams and San Francisco 49ers face each other, while Seattle takes on the Arizona Cardinals. It’s worth noting that the Seahawks’ earlier win over Arizona is what currently keeps them in first place. A loss would drop Seattle […]
Coming off of the bye week, fans of the Los Angeles Rams were 98% confident in this team, but coming after a win over the New Orleans Saints in which the special teams performed poorly again, confidence that the team is headed in the right direction has dropped to 91%. Going from 98% to 91% […]
The San Francisco 49ers’ final injury report is out. Will this be the week Brock Purdy returns to practice? The Niners had a few key defensive starters added to Thursday’s injury report in Keion White, Kalia Davis, Alfred Collins, and Dee Winters. Based on the practice reports leading up to Friday, it was likely that […]
The San Francisco 49ers have a big challenge ahead of them this weekend, as they’ll face the Los Angeles Rams at Levi’s Stadium on Sunday in a big divisional game. So far this season, the 49ers are 3-0 in the division, beating the Rams, Seattle Seahawks, and Arizona Cardinals on the first go around. Now, […]
Trent Williams is a first ballot Hall of Famer. Also, there is an argument for Williams being the greatest left tackle in NFL history. The San Francisco 49ers pulled off a miracle when they traded for Williams following Joe Staley’s retirement announcement. Going from a Hall of Famer to another Hall of Famer at the […]
The Los Angeles Rams will replace kicker Joshua Karty with Harrison Mevis, also known as The Thiccer Kicker, on Sunday in a massive game against the San Francisco 49ers. The move comes after weeks of Rams special teams issues impacting the effectiveness of the team, although some fans question if Karty was actually the problem. […]
The Los Angeles Rams (6-2) are set to travel to the San Francisco 49ers (6-3) on Sunday afternoon; an important game surrounding the NFC West and top-seeds with the NFC Conference. When these two teams played in Week 5, the 49ers jumped out to a quick 14-0 lead; catching the Rams on their heels. LA […]
The 49ers continue to deal with injury issues at wide receiver, as they will likely again be without Ricky Pearsall as well as long-term absentee Brandon Aiyuk for the visit of the Los Angeles Rams on Sunday. San Francisco’s adversity at the pass-catching spots has meant that, for most of the year, the aerial attack […]
The Los Angeles Rams haven’t gotten as much media attention in 2025, despite sitting at 6-2 entering the 49ers matchup. L.A. is best positioned to advance to its third Super Bowl under Sean McVay, something that ESPN predicted in a recent article. In ESPN’s 2025 NFL midseason predictions, reporter Lindsey Thiry anticipates a Rams’ trip […]
It’s another week with the opponent of the Los Angeles Rams having some uncertainty at the quarterback position. Through the first eight games of the season, the Rams have had the benefit of facing two backup quarterbacks and two rookies. In three of those games, the player under center wasn’t the same player who was […]
The Los Angeles Rams will have an opportunity to avenge one of their most disappointing losses of the season when they take on the San Francisco 49ers in Week 10. While the Rams were 8.5-point favorites back in Week 5, they lost in overtime despite having multiple chances to win that game. Much like back […]
The 49ers will look to complete a season sweep of the Los Angeles Rams on Sunday when they host their NFC West rivals at Levi’s Stadium. With the 49ers 3-0 in the division, victory in this battle of six-win teams would serve as a huge step towards San Francisco making the playoffs and potentially recapturing […]
The San Francisco 49ers finished their first orbit around the NFC West with a perfect 3-0 record, a considerable boost to their 6-3 start. The second time around, the division begins with an NFC West two-step, starting on Sunday against the 6-2 Los Angeles Rams in Santa Clara before a Week 11 trip to Arizona. […]
The San Francisco 49ers got the best of the Los Angeles Rams the last time these two teams met in Week 5. San Francisco upset LA on the road under the primetime lights of Thursday Night Football. They’ll square off this weekend as the pecking order in the NFC West division begins to sort itself […]